Opus Magnum has the player take the role of a alchemist to create required products by manipulating atoms of base alchemy elements (the classic elements as well as base metals) through a device they construct within a transmutation engine. The engine is represented as a hex grid which the player arranges various manipulation tools and transmutation spaces on. Manipulators are mechanical arms that rotate around a pivot point, pick up and drop atoms, and rotate structures it currently has picked up, with optional variants that can extend and retract the arm, and/or travel along a track path. Transmutation spaces can create a bond, destroy a bond, transform a basic element into "salt", or upgrade base metals into higher ones using quicksilver. Manipulation parts have a cost to them, though the player is not limited to a total number of manipulation elements, cost, or space the device takes up in crafting their solution.
This article uses material from the Wikipedia article Opus Magnum, https://en.wikipedia.org/wiki/Opus_Magnum_(video_game) which is released under the Creative Commons Attribution-Share-Alike License 3.0, https://creativecommons.org/licenses/by-sa/3.0/.